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. Author manuscript; available in PMC: 2011 Oct 8.
Published in final edited form as: J Neuroimmunol. 2010 Jun 23;227(1-2):153–161. doi: 10.1016/j.jneuroim.2010.06.001

Figure 7.

Figure 7

(A) Effect of whole autistic serum (n=34) on apoptosis of SK-N-SH cells grown to confluency in 96-well culture plates. (B) Effect of autoantibodies to HK-I and VDAC an their competing peptides on apoptosis of SK-N-SH cells grown to confluency in 96-well culture plates. (C) Effect of HK-I or HK-IV on staurosporine induced apoptosis of SK-N-SH cells. Cells were incubated with staurosporine (1.5 μM) in the presence of a single concentration (1 μM) of HK-I or HK-IV in cell culture medium for 6 h prior to the caspase 3/7 activity assay. (D) Effect of anti-HK-I IgG on the protective function of HK-I on staurosporine induced apoptosis. Cells were incubated with staurosporine (1.5 μM) and HK-I (1 μM) in the presence of isolated autistic anti-HK-I IgG (1 μM). * Significantly different from controls (P<0.001).