Table 2.
Laboratory values.
| Active (n = 63) | Placebo (n = 57) | Rank-sum P-value | |||||
|---|---|---|---|---|---|---|---|
| Cytokine | Median baseline value (in pg/ml) | Median percent change (12 weeks) | P-value (signed-rank test) | Median baseline value (in pg/ml) | Median percent change (12 weeks) | P-value (signed-rank test) | |
| GM-CSF | 5.91 | −63.0 | <.0001 | 4.78 | −53.2 | .0007 | .53 |
| IFN-γ | 130.8 | −38.9 | <.0001 | 115.2 | −34.4 | .0011 | .41 |
| IL-2 | 2.13 | −17.6 | .70 | 2.15 | −23.8 | .52 | .96 |
| IL-4 | 6.10 | −50.8 | .001 | 8.26 | −39.4 | .006 | .47 |
| IL-5 | 4.88 | −8.32 | .49 | 4.53 | −30.0 | .66 | .50 |
| IL-6 | 2.19 | −43.2 | .37 | 2.75 | −52.9 | .0963 | .61 |
| IL-8 | 16.3 | −48.4 | <.0001 | 24.1 | −33.0 | .0210 | .21 |
| IL-10 | 6.82 | −70.4 | <.0001 | 5.12 | −49.6 | .0401 | .02 |
| IL-13 | 0.604 | −59.4 | .0104 | 0.500 | −14.4 | .22 | .21 |
| TNF-α | 5.64 | −12.0 | .21 | 7.60 | −21.8 | .0542 | .64 |