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. 2010 Jul 16;285(39):29787–29796. doi: 10.1074/jbc.M110.142620

FIGURE 7.

FIGURE 7.

Locomotor activity in CLAMS cages during 3 h trials, expressed as the ambulatory activity per minute in both the x- and y-dimensions (XY amb) averaged over 15 min intervals. Results are for trials on the first (A and C) and the fourth (B and D) consecutive day, for Gng7−/− mice (KO) and wild-type littermates (WT) on either the C57BL/6 background (A and B) or the BALB/c background (C and D). In a repeated measures MANOVA, day (F1,136 = 108, p < 0.0001), genotype (F1,136 = 7.9, p = 0.006) and background (F1,136 = 85.3, p < 0.0001) were all significant factors, and there was a significant genotype × background interaction (F1,136 = 9.7, p = 0.002). On the BALB/c background, Gng7−/− mice were more active than wild-type littermates on Day 1 (F1,38 = 11.3, p = 0.002).