TABLE 1.
G-protein subunit expression in wild-type and Gng7−/− dorsal striatum as determined by quantitative immunoblotting
| Measured wild type concentration | Formula weight | Calculated wild type concentration | Measured change in Gng7−/− | Calculated change in Gng7−/− | |
|---|---|---|---|---|---|
| ng/μg membrane protein | fmol/μg membrane protein | % | fmol/μg membrane protein | ||
| γ2 | 2.84 ± 0.09 | 7850 | 362 ± 11 | −18 ± 4 | −65 ± 16 |
| γ3 | 0.71 ± 0.10 | 8305 | 85 ± 7 | +39 ± 11 | +33 ± 10 |
| γ7 | 0.65 ± 0.10 | 7611 | 86 ± 8 | −100 | −86 ± 8 |
| β2 | 8.19 ± 0.40 | 37331 | 219 ± 11 | −31 ± 4 | −68 ± 9 |
| αolf | 3.18 ± 0.12 | 44308 | 72 ± 2 | −85 ± 5 | −61 ± 4 |