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. 2010 Jul 7;285(39):29703–29712. doi: 10.1074/jbc.M109.098871

SCHEME 1.

SCHEME 1.

Mechanism for the first committed step during biosynthesis of pentacyclic triterpenoids. The reaction starts with the protonation of oxidosqualene (top) and then involves a series of carbocationic intermediates that first undergo cyclization and then various rearrangements (right) and finally ends by deprotonation into various natural products (left).