. 2010 Aug 4;285(39):29671–29675. doi: 10.1074/jbc.C110.158303

TABLE 2.

Structural features of the homozygous steric zipper interfaces at position 129

	GYMLGS (Met¹²⁹)	GYVLGS (Val¹²⁹)
Origin of PrP sequence	Human 127-132	Human 127-132
Amino acid sequence	GYMLGS	GYVLGS
Surface complementarity (Sc)	0.74	0.75
Surface area buried in interface (Å²)	135 ± 1	119 ± 4
Sheet-to-sheet distance (Å)	9.61 ± 1.24	9.04 ± 2.51^a
Class of steric zipper	Class 8 (antiparallel)	Class 8 (antiparallel)

^a The large S.D. is reflective of the chevron shape of the steric zipper interface, where one end is tightly packed and close together while the other is spread farther apart. The value here is an average of the distance.