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Morphine induces RMOR endocytosis in the VTA. WT and RMOR VTA slices were treated with 30 μm morphine or left untreated (NT) for 25 min. Slices were immunostained for MOR. Morphine induces internalization of the receptor in RMOR but not MOR VTA (both right and left columns). Scale bars, 10 μm.
