. Author manuscript; available in PMC: 2011 Sep 1.

Published in final edited form as: Am J Med Genet B Neuropsychiatr Genet. 2010 Sep;153B(6):1209–1220. doi: 10.1002/ajmg.b.31094

Table V.

Transmethylation metabolites in Arkansas case and control mothers

	Control Mothers (mean ± SD; n=80)	Case Mothers (mean ± SD; n=57)	p-value
Methionine	23.9 ± 4.5	20.9 ± 3.8	0.001
SAM	70.0 ± 12.6	68.7 ± 21.4	NS
SAH	23.9 ± 6.6	32.8 ± 9.9	0.001
SAM/SAH	3.2 ± 1.0	2.3 ± 1.2	0.01
Adenosine	0.27 ± 0.14	0.34 ± 0.17	0.01
Homocysteine	7.24 ± 1.3	9.11 ± 2.1	0.001
Methionine/Homocysteine ratio	3.4 ± 0.80	2.4 ± 0.58	0.001
Folate	17.4 ± 6.2	15.4 ± 3.9	0.05
B12	509 ± 294	449 ± 196	NS

NS: Not significant