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Model 3 is the final modification of Model 1. Where R is recirculation (%), SO2preox is the O2 saturation of the blood entering the oxygenator, SO2postox is the O2 saturation of the blood exiting the oxygenator and SVO2 is the mixed venous O2 saturation in the patient. Notice the modification to correct for the error introduced by recirculation (0.005*R) as well as the addition of a variable to account for the relationship of R and PaO2 (0.163*R*PaO2).
