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. 2010 Feb 4;16(5):999–1009. doi: 10.1089/ten.tec.2009.0394

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Copyright 2010, Mary Ann Liebert, Inc.

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FIG. 5. — Force generation in response to 1 μM acetylcholine (ACh) in (A) bioengineered tissue and (B) native longitudinal tissue. RLSMC sheets generated rapid-rising contractions of 94.4 ± 13.244 μN (n = 7) in response to 1 μM ACh in regular calcium media. Contractions were sustained over a 12-min period. Native longitudinal tissue also generated rapid rising contractions of 53.067 ± 5.014 (n = 6). Addition of ACh is indicated by the arrow at 180 s. Representative tracings for bioengineered constructs and native tissue have been chosen.