Table IV.
Amnestic MCI vs. controls | AD vs. controls | |||||||
---|---|---|---|---|---|---|---|---|
ROC AUC | % MC | Sens/Spec | Power | ROC AUC | % MC | Sens/Spec | Power | |
ERC | 0.74 | 30.1 | 0.75/0.68 | 0.28 | 0.78 | 35.2 | 0.72/0.62 | 0.90 |
Subiculum | 0.72 | 37.0 | 0.70/0.60 | 0.12 | 0.75 | 25.3 | 0.72/0.75 | 0.91 |
CA1 | 0.74 | 28.7 | 0.75/0.70 | 0.51 | 0.80 | 30.0 | 0.67/0.72 | 0.99 |
CA1‐2 transition | 0.83 | 20.5 | 0.85/0.77 | 0.97 | 0.81 | 30.0 | 0.72/0.70 | 0.98 |
Total hippocampus | 0.72 | 31.5 | 0.70/0.68 | 0.35 | 0.75 | 28.7 | 0.61/0.75 | 0.98 |
% MC, percentage of subjects misclassified; Sens/Spec, sensitivity/specificity, AUC, area under the curve of the receiver operating characteristic graphic (ROC); Power, power to the detect a difference between subjects diagnosed with MCI and controls (MCI), respectively, AD and controls (AD) at the significance level alpha = 0.05.
Please see text for ROC and sensitivity/specificity of CA1 in combination with CA1‐2 transition to discriminate between AD and controls.