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. 2010 Sep 21;5(9):e12862. doi: 10.1371/journal.pone.0012862

Table 1. SNPs within the NEMP genes that included significant association with time to AIDS-1987 CDC definition [30].

gene entrez chr score rs pos loc MAF No. SNPs test model OR/RH p unadjusted pGT pST
PECI 10455 6 90.5 rs629362 4066830 intron 0.31 15 DCA A 1.7 6.52×10−6 0.04 0.39
rs853416 4058046 −2880 5′ 0.32 15 DCA A 1.6 3.25×10−5 0.18 1
rs633290 4059787 −1139 5′ 0.31 15 DCA A 1.6 1.66×10−5 0.09 1
rs584585 4063788 intron 0.31 15 DCA A 1.6 1.00×10−5 0.05 0.60
rs659025 4064050 intron 0.31 15 DCA A 1.6 6.12×10−5 0.33 1
rs7744628 4064995 intron 0.31 15 DCA A 1.6 2.15×10−5 0.12 1
rs9503922 4066332 intron 0.26 15 DCA A 1.6 9.52×10−5 0.52 1
rs659305 4070654 intron 0.31 15 DCA A 1.6 1.96×10−5 0.11 1
rs660560 4070940 intron 0.31 15 DCA A 1.6 2.15×10−5 0.12 1
rs661404 4071096 intron 0.40 15 DCA A 1.5 6.40×10−5 0.35 0.35
ACSM4 341392 12 75 rs7961991 7371395 intron 0.16 4 PH R Und 3.59×10−6 0.02 0.22
rs7137120 7346864 −1331 5′ 0.16 4 PH R Und 8.84×10−6 0.05 0.53

Results are from proportional hazards (PH) models or dichotomous categorical analyses (DCA). Chr = chromosome. Score is the haplotype coverage generated by Tagger with the number of SNPs shown for that gene (SNPs) [29]. Pos =  the position from HapMap Project, and build 36. loc =  location relative to the gene. MAF =  Minor allele frequency. R = recessive genetic Model, A = additive genetic model. RH = relative hazard. If the analysis was a DCA, or categorical test, this equates to the Odds Ratio (OR). Und = undefined, which means that there were no cases that succumbed to disease and therefore the value is not statistical calculable. p GT is the p-value corrected for 904 genes and six tests. p ST is the p-value corrected for the number of SNPs and the six tests (see methods).