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. 2010 Sep 21;5(9):e12874. doi: 10.1371/journal.pone.0012874

Figure 4. Immunohistochemical stainings of inflammatory and thrombotic markers.

Figure 4

A) VCAM-1 and ICAM-1 expression of carotid arteries with adjacent CD31 staining. Expression levels of VCAM-1 (B), ICAM-1 (C), thrombomodulin (D) and eNOS (E) in endothelial cells of carotid arteries of irradiated ApoE−/− treated with control chow, NCX 4016 (60 mg/kg/day) or high dose ASA (300 mg/kg/day) containing chow. Bar graphs show the mean expression levels at three positions in the carotid artery: −1; below the bifurcation, 0; at the bifurcation, 1; above the bifurcation and are corrected for the percentage of intact endothelium detected with CD31. Data represents group means ± SEM (n = 10) * Indicates significant differences between high dose ASA and control chow at the same position and # indicates significant difference between position -1 and 1(p<0.05 by Mann-Whitney U test).