Skip to main content
. 2010 Jun;27(6):999–1006. doi: 10.1089/neu.2009.1129

Table 5.

Functional Outcomes on the DRS and NRS-R Based on the Genotypes of NGB on SNPs

Disability Ranking Scale (DRS)
 
rs3783988
rs10133981
  CC + CT (mean ± SD) TT (mean ± SD) p TT + GT (mean ± SD) GG (mean ± SD) p
3 Months 19.70 ± 10.88 12.82 ± 11.30 (n = 153) < 0.01T* 18.80 ± 10.27 14.96 ± 11.61 (n = 151) 0.31T
6 Months 17.90 ± 11.87 11.44 ± 11.88 (n = 150) < 0.01T* 16.75 ± 11.52 13.04 ± 12.15 (n = 147) 0.31T
12 Months 16.31 ± 11.95 10.81 ± 12.48 (n = 131) 0.01T 12.00 ± 11.27 13.00 ± 12.61 (n = 129) 0.81T
24 Months 18.06 ± 13.23 11.47 ± 12.89 (n = 101) 0.02T 13.57 ± 12.33 13.74 ± 13.41 (n = 99) 0.98T
Neurobehavioral Rating Scale-Revised (NRS-R)
 
rs3783988
rs10133981
  CC + CT (mean ± SD) TT (mean ± SD) p TT + GT (mean ± SD) GG (mean ± SD) p
3 Months 41.80 ± 11.12 39.58 ± 9.61 (n = 58) 0.46T 31.50 ± 0.71 40.55 ± 10.01 (n = 58) 0.21T
6 Months 40.90 ± 8.58 41.00 ± 9.42 (n = 74) 0.97T 41.75 ± 13.35 41.03 ± 9.08 (n = 72) 0.88T
12 Months 45.33 ± 15.01 40.02 ± 11.74 (n = 70) 0.12T 35.50 ± 6.46 42.15 ± 13.19 (n = 69) 0.32T
24 Months 40.36 ± 9.11 41.59 ± 9.42 (n = 38) 0.72T 36.67 ± 3.22 41.94 ± 9.45 (n = 37) 0.35T

T, independent t-test; SD, standard deviation; SNP, single nucleotide polymorphism.

*

p < 0.05.