Table 5.
Disability Ranking Scale (DRS) | ||||||
---|---|---|---|---|---|---|
|
rs3783988 |
rs10133981 |
||||
CC + CT (mean ± SD) | TT (mean ± SD) | p | TT + GT (mean ± SD) | GG (mean ± SD) | p | |
3 Months | 19.70 ± 10.88 | 12.82 ± 11.30 | (n = 153) < 0.01T* | 18.80 ± 10.27 | 14.96 ± 11.61 | (n = 151) 0.31T |
6 Months | 17.90 ± 11.87 | 11.44 ± 11.88 | (n = 150) < 0.01T* | 16.75 ± 11.52 | 13.04 ± 12.15 | (n = 147) 0.31T |
12 Months | 16.31 ± 11.95 | 10.81 ± 12.48 | (n = 131) 0.01T | 12.00 ± 11.27 | 13.00 ± 12.61 | (n = 129) 0.81T |
24 Months | 18.06 ± 13.23 | 11.47 ± 12.89 | (n = 101) 0.02T | 13.57 ± 12.33 | 13.74 ± 13.41 | (n = 99) 0.98T |
Neurobehavioral Rating Scale-Revised (NRS-R) | ||||||
---|---|---|---|---|---|---|
|
rs3783988 |
rs10133981 |
||||
CC + CT (mean ± SD) | TT (mean ± SD) | p | TT + GT (mean ± SD) | GG (mean ± SD) | p | |
3 Months | 41.80 ± 11.12 | 39.58 ± 9.61 | (n = 58) 0.46T | 31.50 ± 0.71 | 40.55 ± 10.01 | (n = 58) 0.21T |
6 Months | 40.90 ± 8.58 | 41.00 ± 9.42 | (n = 74) 0.97T | 41.75 ± 13.35 | 41.03 ± 9.08 | (n = 72) 0.88T |
12 Months | 45.33 ± 15.01 | 40.02 ± 11.74 | (n = 70) 0.12T | 35.50 ± 6.46 | 42.15 ± 13.19 | (n = 69) 0.32T |
24 Months | 40.36 ± 9.11 | 41.59 ± 9.42 | (n = 38) 0.72T | 36.67 ± 3.22 | 41.94 ± 9.45 | (n = 37) 0.35T |
T, independent t-test; SD, standard deviation; SNP, single nucleotide polymorphism.
p < 0.05.