Table 1.
Description of the four data sets used in the study
| Data set | Purpose | Study design | Measurements | Subjects |
Analysis |
||||
|---|---|---|---|---|---|---|---|---|---|
| Cases | Controls | Families | Total | Genotyped markers | Imputed markers | ||||
| AGRE | Discovery | Family-based | 550K Illumina | 1,299 | 780 | 3,101 | PDT, X-APL | ||
| ACC | Discovery | Case-control | 550K Illumina | 1,204 | 6,491 | 7,695 | PLINK | SNPTEST | |
| CAP* | Replication | Family-based | 1M Illumina | 504 | 447 | 1,390 | PDT | ||
| CART | Replication | Case-control | 300K Illumina | 108 | 540 | 648 | PLINK | SNPTEST | |
*
The CAP data set has been fully described in ref. 51.