Table 2.
Chr | Bin | cM (Marshfield) | Mb (build 36) | All studies (8), p value |
CD studies (5), p value |
GWAa |
|||
---|---|---|---|---|---|---|---|---|---|
unweighted | weighted | unweighted | weighted | Kb | SNP | ||||
1 | 1_8 | 203–232 | 183–208 | – | 0.0416 | – | – | 190,803 | rs2816316 |
4 | 4_4 | 91–121 | 81–115 | 0.0411 | – | – | – | ||
6 | 6_1 | 0–32 | 0–16 | <0.0001 | <0.0001 | 0.0026 | 0.0012 | ||
6_2 | 32–64 | 16–42 | <0.0001 | <0.0001 | <0.0001 | <0.0001 | |||
6_3 | 64–97 | 42–89 | <0.0001 | <0.0001 | <0.0001 | <0.0001 | 52,573 | rs6936059 | |
8 | 8_5 | 112–140 | 100–129 | 0.0063 | 0.0118 | 0.0484 | – | 103,207 | rs648119 |
9 | 9_3 | 56–84 | 37–85 | 0.0481 | – | – | – | ||
10 | 10_5 | 115–144 | 94–123 | 0.0360 | – | 0.0298 | 0.0369 | ||
10_6 | 144–173 | 123–135 | 0.0027 | 0.0037 | 0.0153 | 0.0227 | |||
11 | 11_5 | 118–148 | 123–134 | 0.0150 | 0.0229 | 0.0407 | – | ||
14 | 14_4 | 83–111 | 74–93 | 0.0208 | 0.0137 | – | – | ||
19 | 19_2 | 26–53 | 8–36 | 0.0121 | – | 0.0037 | 0.0031 | 34,672 | rs1036229 |
Bins with suggestive (p < 0.00847; in bold) and genome-wide (p < 0.00042; in bold and underlined) evidence for linkage are highlighted.
SNPs with p < 10−4 reported in supplementary table 3 from the GWA by van Heel et al. [10].