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. 2010 May 10;38(17):5681–5691. doi: 10.1093/nar/gkq339

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© The Author(s) 2010. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.5), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 4. — Metnase promotes replication fork restart. (A) IdU and CldU labeling scheme is shown above representative confocal microscope images of DNA fibers, with IdU stained red and CldU stained green. (B) Quantification of fiber types. At least 150 fibers were scored per treatment, per cell line for each of three experiments; **P ≤ 0.0014. (C) Fiber lengths were measured by using LSM 510 Image Browser software. Plotted are averages (±SD) of triplicate experiments in which 150–500 fibers were scored per treatment, per experiment. nd, none detected.