Table 1.

Summary of age dependent changes in status epilepticus susceptibility and associated mortality in common murine models of status epilepticus.

Human Developmental stage	Rat age	SE model	SE susceptibility	Mortality	References
Premature newborn	P3–P8	Pilo	Cannot be induced		36, 37
		Li – Pilo	+		40
		KA	+++	+++	38
Full term newborn	P8 – P10	Pilo	+	--	36, 37
		Li – Pilo	+	--	40, 92
		KA	+++	+++	38, 39
		PTZ	+++	--	80, 96
		Hyperthermia-induced SE	+++	--	34, 35
Infant/toddler/pre-adolescence	P11 – P24	Pilo	++	+	37
		Li – Pilo	++	--	40
		KA	+++	+	38, 39
		ES	++	+	32
Adolescent (Prepubescent/pubescent)	P25 – P35	Pilo	+++	+++	37
		Li – Pilo	+++	+++	40
		KA	++	+	38, 39, 78
		PTZ	+++	--	81
		ES	+++	+++	32
Adult	>P60	Pilo	+++	+++	37
		Li – Pilo	+++	+++	20
		KA	+++	+	20, 21, 23, 38

Note: Onset of puberty is from approximately P32-P38 in the rat.