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Sequences and structures of complexes in this study (curved lines indicate ethylene glycol-derived loop replacements of varied length): (A) DNA duplexes with natural (left) and nonnatural (right) loops; (B) DNA triplexes formed between hairpin-type pyrimidine ligands and minimal eight-base purine target strands; (C) similar DNA triplexes formed with longer targets which extend beyond the loop.
