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. Author manuscript; available in PMC: 2011 Jan 1.
Published in final edited form as: Cancer Res. 2009 Dec 22;70(1):181–191. doi: 10.1158/0008-5472.CAN-09-2331

Figure 5. MYC is a target gene of OTX2 in medulloblastoma cell lines.

Figure 5

(A) Expression of endogenous OTX2 and MYC in medulloblastoma cell lines demonstrated by Western blotting. (B) Medulloblastoma cell lines were treated with OTX2 siRNA (+) or scrambled siRNA (−), and protein expression of OTX2, MYC, and GAPDH was detected by Western blotting. (C) Cells were treated with MYC siRNA or scrambled siRNA and after three doubling times assessed for viability with the MTT assay. (D) Medulloblastoma cell lines were treated with MYC siRNA (+) or scrambled siRNA (−), and protein expression of OTX2, MYC, and GAPDH was detected by Western blotting.