Ref (type)	Population	Outcome, Interventions	Results and statistical analysis	Effect size	Favours
Drowsiness
RCT	50 children aged 6 months to 6 years, total of 91 flights assessed	Proportion of children reporting drowsiness take off 30/50 (60%) with pseudoephedrine 11/41 (27%) with placebo	P = 0.003	Effect size not calculated	placebo