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. Author manuscript; available in PMC: 2011 Nov 1.
Published in final edited form as: J Comp Neurol. 2010 Nov 1;518(21):4311–4328. doi: 10.1002/cne.22458

Figure 2. GluN2B subunit immunogold labeling decreased in hippocampal CA1 asymmetric synapses during FZP withdrawal.

Figure 2

(A, B) Representative electron micrographs of GluN2B-labeled asymmetric synapses from control and (C, D) FZP-withdrawn synapses show 10 nm immunogold particles mainly in the postsynaptic density and extending into the synaptic cleft. (E) FZP-withdrawal caused a significant reduction in the total percentage of synapses labeled with at least one immunogold particle compared to controls (***p<0.001) and (F) in mean immunogold density (n=5 rats/group, *p<0.017). As in Figure 1, each dot represents a single animal average (43 to 59 synapses analyzed in each animal, see Table 2) with the total five animals average and SEM superimposed. Scale bar in C represents 0.25 μm. All images are at the same magnification.