TABLE 4. Univariate analysis of local recurrence.
Factor | All patients | Patients with primary disease | ||||
---|---|---|---|---|---|---|
n | Mean LRFS, months | P | n | Mean LRFS, months | P | |
Age | 0.984 | 0.223 | ||||
≤56 years | 14 | 48.7 | 11 | 37.2 | ||
>56 years | 14 | 50.5 | 9 | NA | ||
Sex | 0.121 | 0.062 | ||||
Female | 15 | 55.4 | 12 | NA | ||
Male | 13 | 41.2 | 8 | 34.2 | ||
Presentation | 0.025 | NA | ||||
Primary disease | 20 | 54.2 | NA | NA | ||
Recurrent disease | 8 | 30.6 | NA | NA | ||
Site | 0.036 | 0.038 | ||||
Retroperitoneum | 20 | 53.4 | 14 | NA | ||
Pelvis | 8 | 21 | 6 | 22.1 | ||
Tumor size | 0.8297 | 0.967 | ||||
<10 cm | 14 | 47.6 | 10 | 54.2 | ||
≥10 cm | 14 | 37.5 | 10 | 39.8 | ||
Grade | 0.422 | 0.552 | ||||
I, low | 5 | NA | 3 | NA | ||
II, intermediate, or III, high | 21 | 35.2 | 16 | 39.2 | ||
Histology | 0.761 | 0.281 | ||||
Liposarcoma | 14 | 49.1 | 11 | NA | ||
Nonliposarcoma | 14 | 48.6 | 9 | 51.3 | ||
Number of adjacent organs resected | 0.127 | 0.758 | ||||
0–1 | 15 | 40.8 | 9 | 51.1 | ||
>1 | 13 | 40.7 | 11 | 40.2 | ||
Margin | 0.633 | 0.83 | ||||
Microscopically negative | 13 | 49.6 | 11 | 54.7 | ||
Microscopically or grossly positive | 15 | 47 | 9 | 39.2 | ||
Timing of radiation | 0.506 | 0.435 | ||||
Preop or preop and postop | 22 | 51.4 | 15 | 41 | ||
Only postop | 6 | 42.7 | 5 | 49.1 | ||
Total dose of radiation | 0.563 | 0.962 | ||||
<64 Gy | 14 | 45.7 | 10 | 54.2 | ||
≥64 Gy | 14 | 48.1 | 10 | 40.2 | ||
Adjuvant chemotherapy | 0.287 | 0.58 | ||||
No | 23 | 45.6 | 16 | 52.6 | ||
Yes | 3 | NA | 2 | NA |
LRFS local recurrence-free surviva, preop preoperative, postop postoperative, NA not applicable