Table 4.
Association with Protective Immunity at Week 16
| Characteristic | HBsAb ≥ 10 mIU/mL (n=26) |
HBsAb <10 mIU/mL (n=18) |
p-value |
|---|---|---|---|
| Median age (IQR) | 37 (29, 45) | 45 (40, 54) | 0.03a |
| Gender | 0.46b | ||
| Male (n=34) | 21 (62%) | 13 (38%) | |
| Female (n=10) | 5 (50%) | 5 (50%) | |
| Race/ethnicity | |||
| White (n=24) | 13 (54%) | 11 (46%) | 0.81b |
| Black (n=13) | 9 (69%) | 4 (31%) | |
| Hispanic (n=7) | 4 (57%) | 3 (43%) | |
| Median CD4 cell count (IQR) | |||
| Week 0 | 503 (333, 586) | 364 (246, 463) | 0.15a |
| Nadir | 127 (49, 353) | 143 (93, 250) | 0.75a |
| Baseline CD4 | 0.46b | ||
| <350c/mm3 (n=16) | 8 (50%) | 8 (50%) | |
| ≥350c/mm3 (n=28) | 18 (64%) | 10 (36%) | |
| Nadir CD4 | 0.66b | ||
| <200c/mm3 (n=27) | 15 (56%) | 12 (44%) | |
| ≥200c/mm3 (n=17) | 11 (65%) | 6 (35%) | |
| On HAART at week 0 (n=36) | 21 (58%) | 15 (42%) | 0.89b |
| Week 0 HIV RNA | |||
| Median log10 (IQR) | 1.71 (1.70, 2.02) | 1.78 (1.70, 2.61) | 0.42a |
| <1000 cp/mL (n=37) | 23 (62%) | 14 (38%) | 0.33b |
| <50 cp/mL (n=24) | 15 (63%) | 9 (38%) | 0.59b |
Row percentages presented.
a
Van Elteren’s Test stratified by study arm.
b
Cochran-Mantel-Haenszel Test stratified by study arm.