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. Author manuscript; available in PMC: 2010 Sep 22.
Published in final edited form as: Transplantation. 2008 Jul 15;86(1):75–81. doi: 10.1097/TP.0b013e31817352b9

TABLE 3.

De novo H-Y antibody development and histopathologic correlations in M→F patients with graft dysfunction

Patient characteristics (n=26 M→F) H-Y antibody detected
P
Yes (n=12) No (n=14)
Biopsy assessment
 AR 11 (92%) 3 (21%) 0.00048
 Non-AR 1 (8%) 11 (79%)
 C4d positive 1 (8%) 0 (0%) NS
 CD20+B cells 6 (50%) 3 (21%) NS
 CD138+/CD38+/plasma cells 8 (67%) 3 (21%) 0.04
Clinical assessment
 Delayed graft function 5 (42%) 3 (21%) NS
 DSA positive 2 (17%) 5 (36%) NS
 Graft failure 1 (8%) 2 (14%) NS
 Time of biopsy (d), median (range) 724 (28–3386) 435 (33–3077) NS