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. 2010 Sep 22;5(9):e12819. doi: 10.1371/journal.pone.0012819

Table 1. Binding parameters for the c-Cbl:peptide interactions.

Peptide Sequence kon koff Kd χ2
(M −1s−1) (s−1) (µM)
pSpry2 IRNTNEpYTEGPT 3.7×105 0.139 0.31 4.85
ppSpry2 IRNTNEpYpTEGPT 7.7×104 0.295 3.83 6.68
pEGFR DSFLQRpYSSDPT 2.8×105 0.279 1.00 0.68
ppEGFR DSFLQRpYpSSDPT 6.5×103 0.167 25.8 0.09
tpEGFR DSFLQRpYpSpSDPT 687 0.022 31.5 3.36

χ2 is the statistical error between the experimental and theoretical models. χ2 is defined as Σ (Rf-Rx)2/(n-p), where Rf is the fitted value at a given point, Rx is the experimental value at the same point, n is the number of data points, and p is the number of fitted parameters.