Figure 6. Survivors of Ctgf Hi/+ embryonic lethality.

Gross morphology of high Ctgf-expressing survivors at 10 months old. Males are shown in A) and B) and females are shown in C) and D). In A) and B) the Ctgf Hi/+ mice (foreground) have small ears, shortened face and short body length. B) The short curly tail of the Hi/+ male. D) Short kinked tail and short body of the Hi/+ female (top) compared with a control sibling (bottom). All the animals shown are siblings from a cross between Ctgf Lo/+ and EIIa-Cre +/− animals on a mixed B6.129 background. The controls (background of A) and C) and bottom of D)) are of the genotype Ctgf Lo/+.