Table 2.
<D> [10−3mm2/sec] | FA | Ktrans [min−1] | ve | vp | |
---|---|---|---|---|---|
PCa | 1.07 ± 0.12a,b | 0.20 ± 0.05 | 0.18 ± 0.06a,b | 0.20 ± 0.05c | 0.006 ± 0.008a,b |
PZ | 1.76 ± 0.23b | 0.20 ± 0.06 | 0.06 ± 0.03b | 0.24 ± 0.13c | 0.018 ± 0.012 |
CG | 1.61 ± 0.12 | 0.20 ± 0.03 | 0.11 ± 0.04 | 0.29 ± 0.11 | 0.017 ± 0.009 |
– significantly different than PZ (p<0.001)
– significantly different than CG (p<0.001)
– significantly different than CG (p<0.01)
<D> – mean diffusivity, FA – fractional anisotropy
Ktrans – volume transfer constant, ve – fractional volume of the extra-vascular extra-cellular space, vp – fractional plasma volume
PCa – prostatic adenocarcinoma (DTI: n = 25, DCE MRI: n = 19), PZ – normal peripheral zone (DTI: n = 147, DCE MRI: n = 133), CG – central gland (DTI: n = 40, DCE MRI: n = 40)