Table 1.

Clinical Characteristics of Children with and Without HIV Infection in a Case-Control Study of Biomarkers of Vascular Dysfunction

Variable	Controls (n=55)	HIV + (n=106)	P
Mean (SD) Age, y	12.3 (3.8)	14.8 (4.3)	<0.001
Percent female	43	56	0.14
Race, %			0.04
Black	78	62
Hispanic	18	24
White/other	4	15
Mean (SD) Weight z-score	0.55 (1.2)	0.26 (1.3)	0.17
Mean (SD) Height z-score	0.19 (.98)	−0.46 (1.2)	<0.001
Mean (SD) BMI z-score	0.51 (1.2)	0.51 (1.1)	0.99
Mean (SD) Body fat, %	…	24 (13)
Mean (SD) Trunk fat, %	…	24 (14)
Mean (SD) Waist circumference, cm	…	76 (15)
Mean (SD) Hip circumference, cm	…	86 (15)
Mean (SD) Waist:hip ratio	…	0.89 (0.07)
Disease Characteristics
CDC Stage, %
Stage A	…	22
Stage B	…	34
Stage C	…	39
Stage N	…	6
Mean (SD) CD4, %	…	27 (13)
Median [IQR] Viral load	…	882 [50, 11500]
% Receiving HAART	…	86
Mean (SD) duration of HAART, y	…	6.0 (3.1)
% Receiving Protease Inhibitors	…	80
Mean (SD) duration of PI therapy, y	…	5.0 (3.3)
% Receiving NRTI	…	90
Mean (SD) duration of NRTI, y	…	9.2 (4.6)
% Receiving NNRTI	…	11
Mean (SD) duration of NNRTI therapy, y	…	2.3 (2.6)

IQR = interquartile range; HAART = highly active antiretroviral therapy; NRTI = nucleoside reverse transcriptase inhibitor; NNRTI = non-nucleoside reverse transcriptase inhibitor