Table 1. Transfusion reaction incidence pre- and post-implementation of universal leukoreduction (ULR).

	Pre–universal leukoreduction (n; incidence) 1993-1999	Post–universal leukoreduction (n; incidence) 2001-2007	Odds Ratio Post-/Pre-ULR (95% confidence interval)	Net Change In Incidence	p value (incidence pre/post- ULR)
Transfused Components	362,784	415,775	------	-----	-----
TRALI cases	10 (2.8*)	2 (0.48*)	0.17 (0.04-0.80)	−83%	0.01
TACO cases	27 (7.4*)	16 (3.8*)	0.52 (0.28-0.96)	−49%	0.03
Allergic Reactions	255 (7.0†)	290 (7.0†)	0.99 (0.84-1.17)	0%	0.96
Fever/Rigor Reactions	413 (11.4†)	309 (7.4†)	0.65 (0.56-0.76)	−35%	<0.0001

^*Rate per 100,000 components transfused

^†Rate per 10,000 components transfused