Table 2. TRALI incidence by blood component pre- and post-implementation of universal leukoreduction.
| Pre–universal leukoreduction TRALI (n; incidence) 1993-1999 |
Post–universal leukoreduction TRALI (n; incidence) 2001-2007 |
Odds Ratio Post-/Pre-ULR (95% confidence interval) |
Net Change In Incidence |
|
|---|---|---|---|---|
| Cryoprecipitate (Cryo) |
0 of 19,152 (0) | 0 of 18,870 (0) | Not Applicable | 0% |
| Fresh Frozen Plasma (FFP) |
4 of 56,201 (7.1)* |
1 of 87,744 (1.1)* |
0.16 (0.02 – 1.4) | −85% |
| Red Cells (RBC) |
3 of 147,789 (2.0)* |
1 of 173,244 (0.58*) |
0.28 (0.03 – 2.7) | −71% |
| Platelets | 3 of 139,642 (2.1*) |
0 of 135,917 (0*) |
0.15 (0.008 – 2.8) | −100% |
| Total FFP/Cryo | 4 of 75,353 (5.3)* |
1 of 106,614 (0.94)* |
0.18 (0.02 –1.6) | −82% |
| Total RBC/Platelets |
6 of 287,431 (2.1)* |
1 of 309,161 (0.32)* |
0.16 (0.02 –1.3) | −85% |
*
Rate per 100,000 components transfused