Table 3. TACO incidence by blood component pre- and post-implementation of universal leukoreduction.
| Pre–universal leukoreduction TACO (n; incidence) 1993-1999 |
Post–universal leukoreduction TACO (n; incidence) 2001-2007 |
Odds Ratio Post-/Pre-ULR (95% confidence interval) |
Net Change In Incidence |
|
|---|---|---|---|---|
| Cryoprecipitate (Cryo) |
1 of 19,152 (5.2)* |
0 of 18,870 (0) | 0.33 (0.01 – 8.1) | −100% |
| Fresh Frozen Plasma (FFP) |
2 of 56,201 (3.6)* |
6 of 87,744 (6.8)* |
1.9 (0.39 - 9.5) | +89% |
| Red Cells (RBC) | 19 of 147,789 (12.8)* |
9 of 173,244 (5.2*) |
0.40 (0.18 – 0.89) | −59% |
| Platelets | 5 of 139,642 (3.6*) |
1 of 135,917 (0.74*) |
0.21 (0.02 –1.8) | −79% |
| Total Cryo/FFP | 3 of 75,353 (4.0)* |
6 of 106,614 (5.6)* |
1.4 (0.35 – 5.7) | +40% |
| Total RBC/Platelets |
24 of 287,431 (8.4)* |
10 of 309,161 (3.2)* |
0.39 (0.19 – 0.81) | −62% |
*
Rate per 100,000 components transfused