Table 1.
n | h | S | bp | π | πns | πs | Tajima's D | ZnS | |
Zimbabwe | |||||||||
Entire gene | 10 | 9 | 142 | 3895 | 0.01188 | 0.00367 | 0.02075 | −0.5199 | 0.1321 |
5' gene region | 10 | 9 | 123 | 3213 | 0.01271 | 0.00356 | 0.01934 | −0.4621 | 0.1341 |
Intron 2 | 10 | 8 | 30 | 398 | 0.02903 | n/a | n/a | 0.2622 | 0.1796 |
New York | |||||||||
Entire gene | 18 | 16 | 94 | 3895 | 0.00768 | 0.00343 | 0.00654 | 0.2665 | 0.1462 |
5' gene region | 18 | 16 | 86 | 3213 | 0.00861 | 0.00345 | 0.00862 | 0.2906 | 0.1560*** |
Intron 2 | 18 | 5*** | 15 | 398 | 0.01867*** | n/a | n/a | 2.6697*** | 0.7474* |
New York (“A” group) | |||||||||
Entire gene | 8 | 6 | 64 | 3895 | 0.00564 | 0.00386 | 0.00589 | −0.7286 | 0.2987 |
5' gene region | 8 | 6** | 59 | 3213 | 0.00635 | 0.00434 | 0.00913 | −0.7129*** | 0.312*** |
Intron 2 | 8 | 2* | 3 | 398 | 0.00188** | n/a | n/a | −1.4475* | 1* |
New York (“B” group) | |||||||||
Entire gene | 10 | 10 | 56 | 3895 | 0.00477 | 0.00284 | 0.00493 | −0.3730 | 0.187 |
5' gene region | 10 | 10 | 49 | 3213 | 0.00499 | 0.00285 | 0.00509 | −0.4352 | 0.1869 |
Intron 2 | 10 | 3 | 4 | 398 | 0.00201 | n/a | n/a | −1.6671 | 0.5062 |
NOTE.—n/a, not applicable; n, number of alleles sampled; h, number of haplotypes; S, segregating sites; bp, sequence length in base pairs; π is nucleotide diversity per base pair; ns, nonsynonymous; s, synonymous. The US population was both analyzed as a whole and split into haplotype groups. Tajima's D (Tajima 1989) includes all mutations. ZnS (Kelly 1997) is linkage disequilibrium based on segregating sites. Statistically significant values (*0.01 ≤ P < 0.05; **0.001 ≤ P < 0.01; ***P < 0.001) under a null demographic model are indicated (*) for the 5′ gene region and intron 2 in the New York population and the “A” haplotype group (see table 2).