Table 2.
Distribution of Summary Statistics Based on Simulations under Three Different Demographic Models.
| h | hA | π | πA | f | D | DA | ZnS | ZnSA | |
| Second intron | |||||||||
| Observed: | |||||||||
| eater (US) | 5 | 2 | 7.431 | 0.750 | 0.1009 | 2.6697 | −1.4475 | 0.7474 | 1.0 |
| Simulations | |||||||||
| Null model | 11.31 (9, 14) | 4.91 (3, 8) | 4.56 (3.24, 5.85) | 2.94 (0.93, 5.5) | 0.64 (0.21, 1.15) | 0.18 (−0.68, 1.29) | 0.08 (−1.47, 1.43) | 0.14 (0.09, 0.26) | 0.33 (0.08 ,0.81) |
| P value | 0* | 0.017* | 0* | 0.001* | 0* | 0* | 0.031* | 0* | 0.016* |
| TA | 5.74 (2, 12) | 2.56 (1, 6) | 6.34 (2.92, 7.84) | 1.06 (0, 4.64) | 0.19 (0, 0.75) | 1.72 −1.26, 3.03) | −0.53 (−1.74, 1.91) | 0.55 (0.06, 1) | 0.54 (0.02, 1) |
| P value | 0.547 | 0.534 | 0.872 | 0.549 | 0.5 | 0.1 | 0.272 | 0.235 | 0.261 |
| LS | 9.01 (5, 13) | 3.88 (1, 7) | 5.92 (4.01, 7.18) | 2.3 (0, 5.46) | 0.39 (0, 0.88) | 1.36 (−0.31, 2.45) | −0.31 (−1.64, 1.44) | 0.34 (0.17, 0.65) | 0.43 (0.04, 1) |
| P value | 0.076 | 0.182 | 0* | 0.201 | 0.156 | 0* | 0.091 | 0.018* | 0.077 |
| 5′ gene region | |||||||||
| Observed | |||||||||
| eater (US) | 16 | 6 | 26.74 | 19.75 | 0.74 | 0.2906 | −0.7129 | 0.1560 | 0.312 |
| Simulations | |||||||||
| Null model | 17.39 (15, 18) | 7.8 (7, 8) | 25.47 (22.46, 28.75) | 23.27 (17.64, 28.32) | 0.91 (0.77, 1.06) | 0.08 (−0.43, 0.63) | 0.1 (−0.51, 0.91) | 0.08 (0.07, 0.1) | 0.18 (0.15, 0.24) |
| P value | 0.107 | 0.005* | 0.782 | 0.089 | 0.018* | 0.218 | 0* | 0* | 0* |
| TA | 14.94 (12, 17) | 6.59 (4, 8) | 34.01 (22.6, 40.13) | 19.45 (3.75, 32.46) | 0.58 (0.11, 1.09) | 1.51 (−0.4, 2.53) | −0.01 (−1.87, 1.53) | 0.31 (0.19, 0.52) | 0.44 (0.22, 0.85) |
| P value | 0.851 | 0.396 | 0.059 | 0.495 | 0.713 | 0.941 | 0.238 | 1 | 0.851 |
| LS | 17.28 (14, 18) | 7.58 (6, 8) | 31.46 (26.35, 36.38) | 26.1 (17.18, 32.68) | 0.83 (0.6, 1.07) | 1.08 (0.22, 1.9) | 0.36 (−0.56, 1.22) | 0.12 (0.09, 0.15) | 0.23 (0.17, 0.29) |
| P value | 0.139 | 0.04* | 0.06 | 0.069 | 0.188 | 0.97 | 0.02* | 0.06 | 0* |
NOTE.—Empirical estimates of population genetic statistics are given for the US population and the “A” haplotype group. For the simulated distributions, the means and 95% confidence intervals (in parentheses) under three different demographic models are indicated. TA refers to the model based on Thornton and Andolfatto (2006), and LS refers to the model based on Li and Stephan (2006). π is nucleotide diversity, or average pairwise differences, per locus. f is nucleotide diversity in the putatively selected allele (“A”) divided by the total nucleotide diversity. D is Tajima's D including all mutations. P values indicate the proportion of simulations where the simulated values were more extreme than the empirical estimate at eater. Tests of h, π, D, ZnS were two tailed, and the means were standardized around 0 to calculated P values. f, hA, πA, DA, and ZnSA were used to test for a partial selective sweep, and simulated values were considered extreme if they were less than empirical estimates of f, hA, πA, and DA or greater than empirical estimates of ZnSA.
*p values less than 0.05.