Table 3.
Effect of intervention on primary and secondary endpoints
| Outcomes | 3-Day Routine Change Group (n = 177) |
Clinically Indicated Change Group (n = 185) |
RR (95% CI), P Value |
|---|---|---|---|
| Primary: | |||
| IVD complications per patient, n (%) | 64 (36%) | 76 (41%) | RR 1.14 (0.88, 1.47), p = 0.39 |
| IVD complications per 1000 IVD days | 66.0 (95% CI 49.8, 82.1) |
67.8 (95% CI 52.6, 83.1) |
HR 1.03 (0.74, 1.43), p = 0.86 |
| Secondary: | |||
| Phlebitis, n (%) | 12 (7%) | 18 (10%) | RR 1.44 (0.71, 2.89), p = 0.34 |
| Infiltration, n (%) | 53 (30%) | 61 (33%) | RR 1.10 (0.81, 1.49), p = 0.57 |
| Occlusion, n (%) | 5 (3%) | 4 (2%) | RR 0.77 (0.21, 2.80), p = 0.75 |
| Accidental removal, n (%) | 11 (6%) | 16 (9%) | RR 1.39 (0.66, 2.92), p = 0.43 |
| Local infection | 0 | 0 | - |
| IVD-related BSI, n (%) | 0 | 0 | - |
| IVD costs per patient, AUD$ mean (SD) |
$55.42 ($35.26) | $43.35 ($26.78) |
Mean difference $12.07 (95%CI $5.57, $18.56), p < 0.001 |