Table 1.
Response to radiotherapy according to Phillips and Verhaak classifications
| Response to chemotherapy | Response to radiotherapy | Fisher's exact test |
|||
|---|---|---|---|---|---|
| No | Yes | No | Yes | ||
| Phillips subgroups | |||||
| Mes. | 4 | 7 | 5 | 6 | NS |
| PN | 2 | 3 | 6 | 7 | NS |
| Proliferative | 4 | 2 | 4 | 6 | NS |
| Verhaak subgroups | |||||
| Mes. | 6 | 1 | 2 | 8 | p = 0.01* |
| Neural | 0 | 3 | 1 | 5 | p = 0.03° |
| PN | 3 | 1 | 4 | 3 | NS |
| Classical | 1 | 7 | 8 | 3 | P = 0.02* |
Mes. = Mesenchymal, PN = Proneural
* comparison of the frequencies of response to chemotherapy and to radiotherapy in mesenchymal and classical GBMs
° comparison of the frequency of response to treatment in neural vs. other classes of GBMs