Table 4.
Regression coefficients1 and odds ratios2 (OR) from unadjusted and multivariate linear and logistic regression models of maternal serum log p,p'-DDE and birth weight, gestational age and premature birth
Birth weight (grams) | Gestational age (weeks) | Prematurity | |||||||
---|---|---|---|---|---|---|---|---|---|
Regression | 95% C.I. | p | Regression | 95% C.I. | p | OR | 95% C.I. | p | |
coefficient | coefficient | ||||||||
Unadjusted3model | |||||||||
Greenland | -71.4 | (-114.7; -28.1) | < 0.01 | -0.2 | (-0.4; 0.0) | 0.02 | 1.13 | (0.87; 1.47) | 0.37 |
Kharkiv | -32.2 | (-90.8; 26.4) | 0.28 | -0.2 | (-0.4; 0.0) | 0.09 | 1.43 | (0.72; 2.82) | 0.31 |
Warsaw | -131.3 | (-231.5; -31.1) | 0.01 | -0.5 | (-0.9; -0.1) | 0.02 | 1.45 | (0.73; 2.88) | 0.30 |
Multivariate model3,4 | |||||||||
Greenland | -56 | (-99.5; -12.5) | 0.01 | -0.2 | (-0.4; 0.0) | 0.04 | 1.07 | (0.81; 1.41) | 0.64 |
Kharkiv | -48.9 | (-109.7; 11.9) | 0.12 | -0.2 | (-0.4; 0.0) | 0.06 | 1.60 | (0.75; 3.44) | 0.23 |
Warsaw | -146.9 | (-248.8; -45.0) | 0.01 | -0.6 | (-1; -0.2) | < 0.01 | 2.44 | (0.99; 6.06) | 0.05 |
Multivariate model, with gestational age | |||||||||
Greenland | -39.4 | (-79.0; 0.2) | 0.05 | ||||||
Kharkiv | -30.5 | (-88.7; 27.7) | 0.3 | ||||||
Warsaw | -104.3 | (-202.5; -6.1) | 0.04 |
1Per one unit increase of natural log p,p'-DDE
2Per twofold increase of untransformed p,p'-DDE
3Number of subjects in unadjusted/multivariate models: Greenland birth weight 519/519, gestational age 547/547, prematurity 547/547; Kharkiv birth weight 565/565, gestational age 577/577, prematurity 577/577; Warsaw birth weight 186/186, gestational age 198/198, prematurity 198/198
4Models for birth weight controlled for: smoking status (Greenland); age of mother (Kharkiv); age of mother, mother's BMI (Warsaw);
Models for gestational age controlled for: passive smoking (Greenland); mother's age (Kharkiv); mother's education (Warsaw);
Models for prematurity controlled for: mother's education level, mother's age, mother's BMI, marital status, passive smoking (Greenland); mother's age (Kharkiv); education level, smoking status, marital status, mother's age (Warsaw);