Figure 1.
Ideal tissue stabiliziation/preservation scheme for biomarker analysis. A core needle biospy is immediately placed in a multi-purpose stabilization/preservation solution at room temperature. The fixed biopsy specimen could subsequently undergo cryosectioning, processing in standard formalin or ethanol tissue processors, or flow cytometric analysis. The fixed samples could be archived as frozen sections/blocks or paraffin-embedded blocks. The samples would be compatible with standard protein/nucleic acid methodologies.