Fig. 3.

Effect of lipopolysaccharide (LPS) derived from Escherichia coli on basal [Ca²⁺]_i and [Ca²⁺]_i oscillations in HL-1 cells. A: [Ca²⁺]_i versus time in a single HL-1 cell. Trace shows both inhibition of [Ca²⁺]_i oscillations plus reduction in basal [Ca²⁺]_i. B: [Ca²⁺]_i versus time in a single HL-1 cell. Trace shows only inhibition of [Ca²⁺]_i oscillations. C: [Ca²⁺]_i versus time. Values are means ± SE (n = 30 cells). Horizontal bars show application time of LPS-binding protein (LBP; 10 ng/ml) and of LPS for all traces.