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. 2010 May 13;368(1918):2269–2308. doi: 10.1098/rsta.2010.0050

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© 2010 The Royal Society

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 9. — Nullclines for and . (a) The heavy line is a trajectory initiated by depolarizing the rest state at the intersection of the nullclines from −65 to −25 mV, and the subsequent trajectory in the phase plane closely tracks the faster equilibrating v nullcline and slowly works its way up along the direction of increasing w as the T-current deinactivates (i.e. the availability of T-current, w, increases). (b) The effect of DBS, elevating the v nullcline. (c) The effect of sensorimotor stimulation, SM, which lowers the v nullcline. (Adapted from Rubin & Terman (2004).)

Inline graphic — Nullclines for and . (a) The heavy line is a trajectory initiated by depolarizing the rest state at the intersection of the nullclines from −65 to −25 mV, and the subsequent trajectory in the phase plane closely tracks the faster equilibrating v nullcline and slowly works its way up along the direction of increasing w as the T-current deinactivates (i.e. the availability of T-current, w, increases). (b) The effect of DBS, elevating the v nullcline. (c) The effect of sensorimotor stimulation, SM, which lowers the v nullcline. (Adapted from Rubin & Terman (2004).)