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. 2010 Jun 28;368(1921):3001–3025. doi: 10.1098/rsta.2010.0083

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© 2010 The Royal Society

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 2. — Impact of ionic current variability on cellular electrophysiological biomarkers of arrhythmic risk. Electrophysiological properties are shown in the first column and ionic current properties appear in the first row. Relative sensitivities are depicted in grey code, with white being the colour that indicates the maximum sensitivity of an electrophysiological property. I_CaL, L-type calcium current; I_Kr, the rapid component of the delayed rectifier current; I_Ks, the slow component of the delayed rectifier current; I_K1, inward rectifier potassium current; I_NaK, sodium–potassium pump current; I_NaCa, sodium–calcium exchanger current; G_CaL, maximal conductance of I_CaL; τ_f, slow voltage-dependent inactivation gate time constants of I_CaL; G_Kr, maximal conductance of I_Kr; G_Ks, maximal conductance of I_Ks; τ_Xs, activation time constant of I_Ks; G_K1, maximal conductance of I_K1; G_NaK, maximal activity of the sodium–potassium pump; G_NaCa, maximal activity of the sodium–calcium exchanger.