Table 1.
Pathways Affected by Vinclozolin Altered Genes
| E13 | E14 | E16 | ||||
|---|---|---|---|---|---|---|
| Pathway Name | Impact Factor |
#Genes Altered |
Impact Factor |
#Genes Altered |
Impact Factor |
#Genes Altered |
| Calcium signaling pathway | 4.39 | 1 | 4.80 | 3 | 6.04 | 4 |
| Leukocyte transendothelial migration | 2.75 | 1 | 4.67 | 3 | 5.57 | 3 |
| Neuroactive ligand-receptor interaction | 2.61 | 1 | 0.73 | 2 | 2.33 | 3 |
| Regulation of actin cytoskeleton | 3.03 | 1 | 4.62 | 4 | 3.66 | 1 |
| Focal adhesion | 2.91 | 1 | 5.43 | 3 | 9.86 | 1 |
| MAPK signaling pathway | 1.33 | 2 | 3.67 | 4 | ||
| Gap junction | 10.14 | 4 | 8.32 | 3 | ||
| Cell adhesion molecules (CAMs) | 20.15 | 2 | 264.81 | 3 | ||
| Tight junction | 7.97 | 1 | 6.78 | 3 | ||
| Cytokine-cytokine receptor interaction | 0.76 | 1 | 3.54 | 3 | ||
Impact Factor indicates relative significance of pathways. Impact Factor is generated by KEGG pathway analysis software. Higher values indicate pathways of greater relative significance.