Figure 2. Inhibition of neutrophil oxidative metabolism by different concentrations of S100A8, S100A9 and both proteins together (S100A8/A9).
The inhibition of constitutive (panel A–C) and LPS (5µg/ml) stimulated neutrophil oxidative metabolism (Panel D–F) is presented in percentage of controls with no S100 proteins. A significant main effect of HIV status on S100A8, S100A9 and S100A8/A9 anti-oxidative effect on the constitutive oxidative metabolism (F=34.381, 88.223 and 30.858, p=0.000) and on the LPS stimulated metabolism (F=30.051, 33.595 and 71.181, p=0.000) was found.