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Competitive TNA using domains 1, 3, and 4 as competitors. Rabbit anti-rPA serum (NR-3839), NHP anti-rPA serum (NR-9329), and human anti-AVA serum (AVR801) were tested in a competitive TNA using the indicated purified recombinant domains. Each domain was analyzed for its ability to prevent antibody neutralization of LT in J774.A1 cells. Plotted is the mean ± SEM of percent competition at 600 nM competitor for three independent experiments.
