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. 2010 Jul 2;299(3):H799–H810. doi: 10.1152/ajpheart.00170.2010

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Fig. 4. — CHT^+/− mice exhibit blunted baroreceptor sensitivity. A: averaged HR response (in beats/min) in CHT^+/+ (solid line) and CHT^+/− (dotted line) mice to phenylephrine-induced changes in blood pressure (BP) in anesthetized CHT^+/+ and CHT^+/− mice (P < 0.001, F = 12.76). B: estimation of the baroreflex sensitivity index (ΔHR/Δmean BP) to phenylephrine (20 μg/kg ip). Values are means ± SE; n = 8 mice/genotype. Significance was determined using a one-tailed, unpaired Student's t-test (*P = 0.03).