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Pharmacokinetic parametersa
| Dose (mg/kg) | Cmax (μg/ml) | AUC0-∞ (μg·day/ml) | t1/2 (days) | CL (ml/day/kg) | MRT (days) | V (liters) |
|---|---|---|---|---|---|---|
| 5 | 109 ± 31 | 224 ± 60 | 3.13 ± 1.30 | 1.97 ± 0.61 | 2.76 ± 0.84 | 9.17 ± 5.52 |
| 10 | 211 ± 57 | 423 ± 150 | 3.33 ± 0.70 | 2.36 ± 1.85 | 3.15 ± 0.39 | 10.8 ± 6.5 |
Data represent arithmetic means ± standard deviations.
