TABLE 1.

Levels of lung MPO and ratios of serum/lung KC in rats with different conditions of CA immunosuppression, A. fumigatus infection, and PTX3 treatment^a

Group (n = 4)	MPO (μg/g lung)	KC serum/lung ratio
Sham	31.2 ± 10.2	0.201 ± 0.103
CA	53.5 ± 4.9b	0.027 ± 0.004
CA plus A. fumigatus	67.7 ± 0.7c	0.010 ± 0.001
CA plus A. fumigatus plus PTX3	56.6 ± 10.3d	0.024 ± 0.019

^aLung MPO reported as micrograms per gram of lung, and KC level in serum and lung reported as a ratio. In the Sham group, rats remained untreated. In the CA group, rats were immunosuppressed with CA. In the group CA plus A. fumigatus, rats were immunosuppressed and infected with A. fumigatus conidia and treated with saline. In the group CA plus A. fumigatus plus PTX3, rats were immunosuppressed, infected, and treated with PTX3 at 1.5 mg/kg of body weight. Saline and PTX3 were administered according to schedule iii. Means ± standard deviations are reported for each group. The analysis was performed the 4th day after infection.

^bP < 0.05 compared to Sham.

^cP < 0.05 compared to CA.

^dP < 0.05 compared to CA plus A. fumigatus.