TABLE 3.
Summary of pfnhe-1 ms4760 haplotypes, His/Asp ratios, DNNND copy numbers, and in vitro QN responses (IC50) of 60 field P. falciparum isolates
| His/Asp ratioa | ms4760 haplotype(s) | No. of isolates | No. of DNNND copies | IC50(nM) (mean ± SD) |
|---|---|---|---|---|
| 5:8 | 5, 34 | 3 | 4 | 462 ± 123 |
| 5:6 | 7 | 31 | 3 | 661 ± 374 |
| 6:6 | 14 | 1 | 3 | 767 |
| 7:6 | 9 | 2 | 3 | 837 ± 372 |
| 5:4 | 6 | 10 | 2 | 580 ± 254 |
| 7:4 | 1, 18 | 9 | 2 | 312 ± 115 |
| 5:2 | 35 | 1 | 1 | 260 |
| 6:2 | 3 | 3 | 1 | 223 ± 106 |
a
ms4760 haplotypes found among the China-Myanmar border parasite population are grouped here by His/Asp ratios, which are arranged from low to high values.