TABLE 3.

The drug levels in serum and brain tissue measured by bioassay on day 10 of the therapy and 4 h after final dosing^a

Drug and dose (mg/kg)	Serum (μg/ml)	Brain (μg/g)
PSC
10	5.75 ± 1.86	3.08 ± 0.36
20	6.73 ± 1.29	3.64 ± 0.91
40	8.83 ± 0.79	7.41 ± 1.12
VRC
10	4.09 ± 0.98	2.62 ± 0.42
40	5.54 ± 1.55	4.12 ± 0.97
60	7.16 ± 2.13	6.47 ± 1.03
AMB
1.5	6.52 ± 1.47	4.46 ± 0.73

^aResults are expressed as the means ± standard deviations.