TABLE 2.
Thermostability of the antimicrobials with incubation for 24 h at 45°C as powders as well as in solution
| Strain | Antibiotic | Median (range) MIC50 (mg/liter) |
||
|---|---|---|---|---|
| Standard | After incubation with antimicrobial agenta |
|||
| As powder | In solution | |||
| S. aureus | Cefamandole | 0.25 (0.25-0.25) | 0.25 (0.25-0.25) | 0.5 (0.25-0.5) |
| ATCC | Fosfomycin | 0.5 (0.25-1) | 1 (0.5-1) | 0.5 (0.5-1) |
| 29213 | Tigecycline | 1 (1-1) | 1 (1-1) | 1 (1-1) |
| Vancomycin | 0.5 (0.5-2) | 0.5 (0.5-1) | 1 (0.5-1) | |
| Daptomycin | 0.25 (0.25-0.5) | 0.5 (0.5-1) | 1 (0.5-1) | |
| S. epidermidis | Cefamandole | 1 (1-2) | 1 (1-2) | 2 (1-2) |
| OR1 | Fosfomycin | 32 (16-32) | 32 (32-32) | 32 (16-32) |
| Tigecycline | 1 (1-2) | 1 (1-1) | 2 (1-2) | |
| Vancomycin | 2 (2-2) | 2 (1-2) | 2 (1-2) | |
| Daptomycin | 0.5 (0.25-1) | 0.5 (0.5-1) | 1 (0.5-1) | |
a
Incubation was for 24 h at 45°C.